in 2021, the animal husbandry and Veterinary Bureau of the Ministry of agriculture and rural areas issued a notice on promoting the reduction and substitution of corn soybean meal, focusing on the "reduction and substitution of corn soybean meal in feed". It is reported that the demand for protein feed in China in 2010 was 60 million tons, the supply was 22 million tons, and the gap was 38 million tons; By 2020, China's demand will be 72 million tons, and the supply will be 24 million tons, and the gap will rise to 48 million tons! The protein feed gap has increased instead of decreasing, and the supply situation is severe. According to a report released by the United Nations, the global population will increase to 9.6 billion by 2050, and the global food system will need to meet the dietary needs of 9.6 billion people. By 2050, the demand for meat will exceed 400 million tons and the demand for dairy products will exceed 800 million tons to meet the global demand for animal derived protein at the current consumption level. Asner and Archer reported in 2010 that only 20% of the world's agricultural land is used to produce food directly for human consumption, while 80% of the agricultural land is used for animal breeding. More than 1 / 3 of the grain harvest is used for animal feed production. China is a large feed country and a populous country. By 2050, the land space limitation of food increment and the phenomenon of feed competition for grain are intensifying. With the development of the industry and the continuous increase of feed production, the gap between supply and demand of protein feed is becoming larger and larger. In 2018, the food and Agriculture Organization of the United Nations estimated that the output of aquaculture would reach 201 million tons by 2030, and the amount of protein required for fish farming would increase by 10% every year. However, fish meal products were basically stable at 5 million tons per year (International fish meal and Oil Association). By 2050, the world will need up to 15million tons of new protein sources for aquaculture. Marine products such as fish meal and oil are limited, and adding some plant proteins to replace marine products cannot solve the fundamental problem from the perspective of sustainable development. In the future, people's average wealth will exceed today's level, and the quality of the population and awareness of environmental protection will also be greatly improved. Therefore, in the future, food must be produced in a sustainable way, which will help reduce climate change and other environmental challenges. With the increasing demand for sustainable food development, reducing competition with human food resources will be the key to sustainable development, which requires microorganisms to play an important role. Because microorganisms grow fast, microorganisms can convert non food biomass that reduces its value into high-quality feed raw materials, and there is little demand for cultivated land, water and climatic conditions (Overland et al., 2018). Human beings are more and more willing to use microbial feed in aquaculture and agricultural production, which is a potential sustainable feed raw material for aquaculture and livestock and poultry breeding. The main battlefield of biotechnology revolution in the 21st century is big agriculture. To carry out the new agricultural science and technology revolution, we should take bioengineering as the center, reform traditional agriculture and create new agriculture. The development of microbial new agriculture is the main embodiment of the promotion of agricultural development by bioengineering technology. Develop a new type of microbial agriculture, a traditional agriculture with a "two-dimensional structure" mainly composed of plant and animal resources, and a new agriculture with a "three-dimensional structure" adjusted to plant planting, animal breeding and microbial fermentation and transformation, which is a resource-saving agriculture with a sound industrial structure; In addition, white agriculture is a soil-saving and water-saving agriculture, which can alleviate the increasingly acute contradiction between traditional agriculture and "competing for land" and "competing for water". A plant with a small area and an annual output of 100000 tons of SCP produces protein equivalent to the protein of soybeans produced by 37500hm2 of cultivated land in one year. The development of white agriculture can achieve the goal of "sharing grain between people and animals" and greatly alleviate the problem of food shortage. The microbial feed protein of white agriculture provides a guarantee for the development of animal husbandry. Icellscp not only makes up for the global supply gap of high-quality protein, but also effectively reduces carbon emissions, improves environmental performance, accelerates the development of environmental protection, realizes nutrition and water recycling, and promotes the sustainable development of human society. 
